A 14-year-old boy is fighting for his life in hospital after the ute he was in rolled over and hit a number of trees at Carrajung, in eastern Victoria.

The ute was travelling south along Carrajung Woodside Road when the 39-year-old driver, from Woodside, lost control on Saturday afternoon.

There were five people in the a car at the time.

The boy was flown to hospital in Melbourne in a critical condition.

The driver also suffered serious injuries in the crash, while two other boys aged 14 and 15, and a 41-year-old woman were also hurt.